International Journal of Research and Analysis in Science and Engineering

Computational Insight into Binding Affinity and Drug-Likeness of Synthesized Schiff Base and Its Transition Metal Complexes

Dr. Sulakshna Bharti — 2026-03-31

Schiff bases were crucial to the advancement of inorganic, bioinorganic, and optical materials as well as the creation of coordination chemistry. Most of the more frequently used types of organic compounds are Schiff bases, which are extensively utilized in inorganic, organic, and analytical chemistry. Schiff base ligands are very valuable because they can form stable metal complexes with a variety of transition and other metal ions. Schiff bases are produced when a primary amine condenses with an aldehyde or ketone. With an emphasis on structure-activity connections, the biological activity of these complexes is examined, including their antibacterial, anticancer, antioxidant, and enzyme inhibitory qualities. The review also emphasizes the therapeutic potential of these complexes, stressing their use in drug development as well as their difficulties and opportunities in medicinal chemistry. We will talk about this in this paper. Computational Understanding of Synthesized Schiff Base and Its Transition Metal Complexes' Binding Affinity and Drug-Likeness.

Modeling the Relationship Between Cognitive Load and Psychological Latency in Human Information Processing

Dr. Abhishek Kumar — 2026-03-31

This study examines the relationship between psychological latency and cognitive load in human information processing. Psychological latency refers to the time delay between the presentation of a stimulus and the production of a response, while cognitive load represents the amount of mental effort required to process information. Drawing from cognitive psychology, working memory theory, and decision‑making research, this paper proposes a conceptual framework linking task complexity, cognitive load, working memory processes, and response latency. The study highlights how increasing task complexity raises cognitive demand, which in turn affects attention, memory retrieval, and decision speed. The framework provides implications for education, workplace design, healthcare decision systems, and human–computer interaction. By integrating classical theories with modern cognitive research, the paper contributes a structured conceptual model for understanding how mental workload influences human response time and performance.

Relationships Between the Gomti River's Hazardous Inorganic Pollutants and Their Build-Up in Specific Macrophytes in an Aquatic Environment

Dr. Anuradha Singh — 2026-03-31

The Gomti River's water quality and the native macrophytes that live there at six different locations were assessed for their potential for phytoremediation. High levels of nitrate, ammonium, phosphate, chemical oxygen demand, and biochemical oxygen demand were found in river water (12.84, 77.94, 36.88, 6.04, and 2.25 mg L-1, respectively). Several elements, including Fe, Cd, Cu, Cr, and Pb (5.54, 1.05, 3.74, 2.57, and 0.73 mg L-1, respectively), were discovered to be present in Gomti water. Significant concentrations of Fe, Cd, Cu, Cr, and Pb were deposited in various areas by macrophytes growing in the river. Jussiaea repens for Cr, Pistia stratiotes for Cd, and Eichhornia crassipes for Fe, Cd, and Pb demonstrated the highest remediation capacity among the plants under study. On the other hand, Cu buildup peaked in Typha latifolia. The translocation factor of E. crassipes, P. stratiotes, Hydrilla verticellata, and T. latifolia was [1] for the metals under study, with the exception of Fe, indicating their capacity to collect several metals in several plant sections.